Varaico: Literature-Extracted Genetic Variants

KDM4C

135 papers

RefSeq Summary

This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated for...

Pfam Domains

JmjNaa 17–51UCSCjmjN domain

JmjCaa 177–293UCSCJmjC domain, hydroxylase

PHD_2aa 712–747UCSCPHD-finger

zf-HC5HC2H_2aa 753–864UCSCPHD-zinc-finger like domain

Gene Aliases

HGNC Name

lysine demethylase 4C

HGNC Previous Symbol

JMJD2C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_015061.6

p.D852D

c.2556C>T

Surrounding Variants

1 paper

NM_015061.6

p.A844fs

c.2530_2531fs

1 paper

NM_015061.6

p.P833L

c.2498C>T

1 paper

NM_015061.6

p.G822E

c.2465G>A

2 papers

NM_015061.6

p.R816Q

c.2447G>A