Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

1–12 of 2760 variants

217 papers

NM_002253.4

p.Q472H

c.1416A>T

195 papers

NM_002253.4

p.Q472H

c.1416A>C

82 papers

NM_002253.4

p.V297I

c.889G>A

54 papers

NM_002253.4

p.C482R

c.1444T>C

34 papers

NM_002253.4

p.A573A

c.1719A>T

28 papers

NM_002253.4

p.V398I

c.1192G>A

23 papers

NM_002253.4

p.A1065T

c.3193G>A

20 papers

NM_002253.4

p.R961W

c.2881C>T

18 papers

NM_002253.4

p.K266_H267Splc

c.798+54G>A

18 papers

NM_002253.4

p.R1032Q

c.3095G>A

14 papers

NM_002253.4

p.R347H

c.1040G>A

13 papers

NM_002253.4

p.T771R

c.2312C>G