Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

23 papers

NM_002253.4

p.A1065T

c.3193G>A

Surrounding Variants

1 paper

NM_002253.4

p.A1065P

c.3193G>C

1 paper

NM_002253.4

p.D1064_A1065Splc

c.3193-2A>T

4 papers

NM_002253.4

p.R1066C

c.3196C>T

6 papers

NM_002253.4

p.R1066H

c.3197G>A

1 paper

NM_002253.4

p.R1066R

c.3198C>T

2 papers

NM_002253.4

p.P1068S

c.3202C>T

1 paper

NM_002253.4

p.L1069F

c.3207G>T

1 paper

NM_002253.4

p.L1069F

c.3207G>C

1 paper

NM_002253.4

p.L1069L

c.3207G>A

1 paper

NM_002253.4

p.W1071*

c.3212G>A

1 paper

NM_002253.4

p.W1071*

c.3213G>A

1 paper

NM_002253.4

p.M1072I

c.3216G>T