Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.D1056N

c.3166G>A

Surrounding Variants

1 paper

NM_002253.4

p.P1057fs

c.3169_3170fs

5 papers

NM_002253.4

p.Y1054F

c.3161A>T

1 paper

NM_002253.4

p.P1057delFs

c.3170delG

1 paper

NM_002253.4

p.I1053M

c.3159T>G

2 papers

NM_002253.4

p.I1053F

c.3157A>T

1 paper

NM_002253.4

p.I1053L

c.3157A>C

7 papers

NM_002253.4

p.Y1059F

c.3176A>T

1 paper

NM_002253.4

p.D1052G

c.3155A>G

6 papers

NM_002253.4

p.D1052N

c.3154G>A

1 paper

NM_002253.4

p.V1060I

c.3178G>A

9 papers

NM_002253.4

p.R1051Q

c.3152G>A

3 papers

NM_002253.4

p.R1051W

c.3151C>T