Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.E1038V

c.3113A>T

Surrounding Variants

4 papers

NM_002253.4

p.S1037L

c.3110C>T

1 paper

NM_002253.4

p.S1037T

c.3109T>A

1 paper

NM_002253.4

p.N1040K

c.3120C>G

1 paper

NM_002253.4

p.N1040K

c.3120C>A

6 papers

NM_002253.4

p.V1041M

c.3121G>A

1 paper

NM_002253.4

p.V1042F

c.3124G>T

1 paper

NM_002253.4

p.V1042I

c.3124G>A

1 paper

NM_002253.4

p.V1042G

c.3125T>G

1 paper

NM_002253.4

p.V1042A

c.3125T>C

1 paper

NM_002253.4

p.I1034T

c.3101T>C

18 papers

NM_002253.4

p.R1032Q

c.3095G>A

9 papers

NM_002253.4

p.R1032*

c.3094C>T