Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_002253.4

p.S984T

c.2951G>C

Surrounding Variants

1 paper

NM_002253.4

p.S984G

c.2950A>G

1 paper

NM_002253.4

p.D985G

c.2954A>G

1 paper

NM_002253.4

p.L983F

c.2947C>T

1 paper

NM_002253.4

p.L983I

c.2947C>A

2 papers

NM_002253.4

p.S982F

c.2945C>T

2 papers

NM_002253.4

p.K981N

c.2943G>T

1 paper

NM_002253.4

p.E987*

c.2959G>T

2 papers

NM_002253.4

p.K981N

c.2943G>C

1 paper

NM_002253.4

p.E987K

c.2959G>A

1 paper

NM_002253.4

p.E987G

c.2960A>G

1 paper

NM_002253.4

p.K981R

c.2942A>G

1 paper

NM_002253.4

p.E987D

c.2961A>T