Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.V957A

c.2870T>C

Surrounding Variants

1 paper

NM_002253.4

p.D958fs

c.2872_2873fs

1 paper

NM_002253.4

p.D958N

c.2872G>A

1 paper

NM_002253.4

p.P956L

c.2867C>T

1 paper

NM_002253.4

p.P956H

c.2867C>A

2 papers

NM_002253.4

p.P956S

c.2866C>T

1 paper

NM_002253.4

p.L959V

c.2875C>G

1 paper

NM_002253.4

p.L959P

c.2876T>C

1 paper

NM_002253.4

p.I955F

c.2863A>T

2 papers

NM_002253.4

p.I955V

c.2863A>G

20 papers

NM_002253.4

p.R961W

c.2881C>T

1 paper

NM_002253.4

p.G953G

c.2859A>G

2 papers

NM_002253.4

p.R961Q

c.2882G>A