Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_002253.4

p.R946H

c.2837G>A

Surrounding Variants

4 papers

NM_002253.4

p.R946C

c.2836C>T

5 papers

NM_002253.4

p.G948W

c.2842G>T

1 paper

NM_002253.4

p.G948R

c.2842G>C

1 paper

NM_002253.4

p.G948R

c.2842G>A

2 papers

NM_002253.4

p.G948V

c.2843G>T

5 papers

NM_002253.4

p.R944Q

c.2831G>A

2 papers

NM_002253.4

p.R944*

c.2830C>T

1 paper

NM_002253.4

p.A943E

c.2828C>A

1 paper

NM_002253.4

p.K949I

c.2846A>T

1 paper

NM_002253.4

p.G942G

c.2826G>A

3 papers

NM_002253.4

p.G942E

c.2825G>A

1 paper

NM_002253.4

p.G942W

c.2824G>T