Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_002253.4

p.R787W

c.2359C>T

Surrounding Variants

7 papers

NM_002253.4

p.R787Q

c.2360G>A

1 paper

NM_002253.4

p.R787R

c.2361G>A

1 paper

NM_002253.4

p.T788A

c.2362A>G

1 paper

NM_002253.4

p.I785I

c.2355C>T

1 paper

NM_002253.4

p.V789I

c.2365G>A

1 paper

NM_002253.4

p.K790Q

c.2368A>C

1 paper

NM_002253.4

p.V783V

c.2349C>A

1 paper

NM_002253.4

p.R791P

c.2372G>C

5 papers

NM_002253.4

p.R791Q

c.2372G>A

1 paper

NM_002253.4

p.R791_A792Splc

c.2373+1G>T

2 papers

NM_002253.4

p.R791_A792Splc

c.2373+1G>A

1 paper

NM_002253.4

p.L781ins5

c.2341_2342ins15