Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_002253.4

p.T771K

c.2312C>A

Surrounding Variants

7 papers

NM_002253.4

p.T771M

c.2312C>T

13 papers

NM_002253.4

p.T771R

c.2312C>G

1 paper

NM_002253.4

p.A772T

c.2314G>A

1 paper

NM_002253.4

p.G770V

c.2309G>T

1 paper

NM_002253.4

p.G770D

c.2309G>A

6 papers

NM_002253.4

p.A772V

c.2315C>T

1 paper

NM_002253.4

p.V769A

c.2306T>C

1 paper

NM_002253.4

p.V769L

c.2305G>T

1 paper

NM_002253.4

p.V769L

c.2305G>C

1 paper

NM_002253.4

p.V769I

c.2305G>A

1 paper

NM_002253.4

p.L768I

c.2302C>A

1 paper

NM_002253.4

p.A775S

c.2323G>T