Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.W570R

c.1708T>A

Surrounding Variants

1 paper

NM_002253.4

p.W570R

c.1708T>C

1 paper

NM_002253.4

p.L569F

c.1707G>T

1 paper

NM_002253.4

p.L569F

c.1707G>C

2 papers

NM_002253.4

p.W570*

c.1709G>A

2 papers

NM_002253.4

p.W570*

c.1710G>A

1 paper

NM_002253.4

p.T572I

c.1715C>T

1 paper

NM_002253.4

p.V567A

c.1700T>C

1 paper

NM_002253.4

p.E565_S566del2

c.1693_1697del6

1 paper

NM_002253.4

p.A573S

c.1717G>T

9 papers

NM_002253.4

p.V567M

c.1699G>A

34 papers

NM_002253.4

p.A573A

c.1719A>T

1 paper

NM_002253.4

p.A573A

c.1719A>G