Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.L555F

c.1665G>T

Surrounding Variants

1 paper

NM_002253.4

p.L555F

c.1665G>C

1 paper

NM_002253.4

p.Q556H

c.1668A>T

1 paper

NM_002253.4

p.Q556H

c.1668A>C

1 paper

NM_002253.4

p.P557H

c.1670C>A

1 paper

NM_002253.4

p.M559L

c.1675A>T

1 paper

NM_002253.4

p.M559L

c.1675A>C

1 paper

NM_002253.4

p.M559R

c.1676T>G

1 paper

NM_002253.4

p.P551S

c.1651C>T

1 paper

NM_002253.4

p.R549K

c.1646G>A

1 paper

NM_002253.4

p.R549W

c.1645A>T

2 papers

NM_002253.4

p.R549Splc

c.1646-2A>T

1 paper

NM_002253.4

p.Q564L

c.1691A>T