Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

195 papers

NM_002253.4

p.Q472H

c.1416A>C

Surrounding Variants

217 papers

NM_002253.4

p.Q472H

c.1416A>T

2 papers

NM_002253.4

p.Q472R

c.1415A>G

1 paper

NM_002253.4

p.A473V

c.1418C>T

1 paper

NM_002253.4

p.V474F

c.1420G>T

1 paper

NM_002253.4

p.V474L

c.1420G>C

1 paper

NM_002253.4

p.S471Splc

c.1413-1G>A

1 paper

NM_002253.4

p.S475L

c.1424C>T

7 papers

NM_002253.4

p.V476L

c.1426G>T

7 papers

NM_002253.4

p.V476L

c.1426G>C

1 paper

NM_002253.4

p.V476A

c.1427T>C

1 paper

NM_002253.4

p.S471Splc

c.1413-10T>C

3 papers

NM_002253.4

p.P479S

c.1435C>T