Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.T397I

c.1190C>T

Surrounding Variants

1 paper

NM_002253.4

p.T397S

c.1190C>G

1 paper

NM_002253.4

p.T397fs

c.1189_1190fs

1 paper

NM_002253.4

p.T393_Y396del4

c.1177_1187del12

1 paper

NM_002253.4

p.T397S

c.1189A>T

1 paper

NM_002253.4

p.V398L

c.1192G>C

28 papers

NM_002253.4

p.V398I

c.1192G>A

1 paper

NM_002253.4

p.Y396_T397del2

c.1186_1190del6

2 papers

NM_002253.4

p.V398A

c.1193T>C

1 paper

NM_002253.4

p.Y396C

c.1187A>G

1 paper

NM_002253.4

p.D392_N395del4

c.1174_1184del12

1 paper

NM_002253.4

p.R391_V398del8

c.1171_1193del24

1 paper

NM_002253.4

p.G394G

c.1182A>C