Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.M386_T393del8

c.1156_1178del24

Surrounding Variants

1 paper

NM_002253.4

p.G394R

c.1180G>C

1 paper

NM_002253.4

p.G394R

c.1180G>A

1 paper

NM_002253.4

p.G394E

c.1181G>A

1 paper

NM_002253.4

p.S389_D392del4

c.1165_1175del12

1 paper

NM_002253.4

p.G394G

c.1182A>C

1 paper

NM_002253.4

p.D392fs

c.1174_1175fs

1 paper

NM_002253.4

p.D392delFs

c.1174_1175delTC

1 paper

NM_002253.4

p.D392_N395del4

c.1174_1184del12

3 papers

NM_002253.4

p.D392N

c.1174G>A

1 paper

NM_002253.4

p.Y396C

c.1187A>G

1 paper

NM_002253.4

p.T397S

c.1189A>T

1 paper

NM_002253.4

p.T397I

c.1190C>T