Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.T384T

c.1152G>A

Surrounding Variants

1 paper

NM_002253.4

p.M386T

c.1157T>C

1 paper

NM_002253.4

p.L383M

c.1147C>A

1 paper

NM_002253.4

p.T376_V382del7

c.1126_1145del21

1 paper

NM_002253.4

p.G380_H381del2

c.1138_1142del6

1 paper

NM_002253.4

p.E387K

c.1159G>A

1 paper

NM_002253.4

p.I385_M386del2

c.1153_1157del6

1 paper

NM_002253.4

p.T384_M386del3

c.1150_1157del9

1 paper

NM_002253.4

p.I377_H381del5

c.1129_1142del15

1 paper

NM_002253.4

p.E387D

c.1161A>T

1 paper

NM_002253.4

p.H381_V382insA

c.1141_1145ins3

1 paper

NM_002253.4

p.I377_G380del4

c.1129_1139del12

1 paper

NM_002253.4

p.N374_G380del7

c.1120_1139del21