Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002253.4

p.T376A

c.1126A>G

Surrounding Variants

1 paper

NM_002253.4

p.N374_H375del2

c.1120_1124del6

1 paper

NM_002253.4

p.H375_T376del2

c.1123_1127del6

1 paper

NM_002253.4

p.N374_H375insT

c.1120_1124ins3

2 papers

NM_002253.4

p.S373F

c.1118C>T

2 papers

NM_002253.4

p.K378N

c.1134A>T

2 papers

NM_002253.4

p.K378N

c.1134A>C

1 paper

NM_002253.4

p.S373_N374insT

c.1117_1121ins3

1 paper

NM_002253.4

p.L371_K378del8

c.1111_1133del24

3 papers

NM_002253.4

p.E372D

c.1116G>T

3 papers

NM_002253.4

p.E372D

c.1116G>C

1 paper

NM_002253.4

p.A379V

c.1136C>T

1 paper

NM_002253.4

p.G380W

c.1138G>T