Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.P359_I362del4

c.1075_1085del12

Surrounding Variants

1 paper

NM_002253.4

p.E361_I362del2

c.1081_1085del6

1 paper

NM_002253.4

p.I362_K363insG

c.1084_1088ins3

1 paper

NM_002253.4

p.Y357_E361del5

c.1069_1082del15

1 paper

NM_002253.4

p.W364L

c.1091G>T

1 paper

NM_002253.4

p.E361G

c.1082A>G

1 paper

NM_002253.4

p.G356_P360del5

c.1066_1079del15

1 paper

NM_002253.4

p.K353_P360del8

c.1057_1079del24

1 paper

NM_002253.4

p.L355_P359del5

c.1063_1076del15

1 paper

NM_002253.4

p.P360_E361insT

c.1078_1082ins3

3 papers

NM_002253.4

p.P359H

c.1076C>A

1 paper

NM_002253.4

p.P358L

c.1073C>T

2 papers

NM_002253.4

p.Y357N

c.1069T>A