Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_002253.4

p.G345R

c.1033G>C

Surrounding Variants

2 papers

NM_002253.4

p.G345W

c.1033G>T

3 papers

NM_002253.4

p.G345R

c.1033G>A

1 paper

NM_002253.4

p.V344A

c.1031T>C

1 paper

NM_002253.4

p.T343T

c.1029G>A

1 paper

NM_002253.4

p.V344_G345del2

c.1030_1034del6

1 paper

NM_002253.4

p.T343M

c.1028C>T

5 papers

NM_002253.4

p.R347C

c.1039C>T

1 paper

NM_002253.4

p.R347_V348ins4

c.1039_1043ins12

1 paper

NM_002253.4

p.V344_E346del3

c.1030_1037del9

14 papers

NM_002253.4

p.R347H

c.1040G>A

1 paper

NM_002253.4

p.A342V

c.1025C>T

1 paper

NM_002253.4

p.A342S

c.1024G>T