Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.T320I

c.959C>T

Surrounding Variants

1 paper

NM_002253.4

p.F321_V322ins4

c.961_965ins12

1 paper

NM_002253.4

p.S311_T320del10

c.931_959del30

1 paper

NM_002253.4

p.S319N

c.956G>A

1 paper

NM_002253.4

p.T315_N318del4

c.943_953del12

1 paper

NM_002253.4

p.V322F

c.964G>T

1 paper

NM_002253.4

p.N318K

c.954C>G

1 paper

NM_002253.4

p.N318K

c.954C>A

1 paper

NM_002253.4

p.K316_K317del2

c.946_950del6

1 paper

NM_002253.4

p.K317insFs

c.949_950insA

1 paper

NM_002253.4

p.A309_V322del14

c.925_965del42

1 paper

NM_002253.4

p.K317M

c.950A>T

1 paper

NM_002253.4

p.L304_K316del13

c.910_947del39