Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.Y305*

c.915C>G

Surrounding Variants

1 paper

NM_002253.4

p.Y305*

c.915C>A

1 paper

NM_002253.4

p.Q302_Y305del4

c.904_914del12

1 paper

NM_002253.4

p.G296_Y305del10

c.886_914del30

1 paper

NM_002253.4

p.Q302_L304del3

c.904_911del9

1 paper

NM_002253.4

p.Y305fs

c.913_914fs

1 paper

NM_002253.4

p.T298_G303ins2

c.892_909dup18

1 paper

NM_002253.4

p.Q302_C307del6

c.904_920del18

1 paper

NM_002253.4

p.G303R

c.907G>A

1 paper

NM_002253.4

p.T306_A308del3

c.916_923del9

1 paper

NM_002253.4

p.A309E

c.926C>A

1 paper

NM_002253.4

p.Q302K

c.904C>A

1 paper

NM_002253.4

p.S300_D301del2

c.898_902del6