Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.V297G

c.890T>G

Surrounding Variants

3 papers

NM_002253.4

p.V297L

c.889G>T

3 papers

NM_002253.4

p.V297L

c.889G>C

82 papers

NM_002253.4

p.V297I

c.889G>A

1 paper

NM_002253.4

p.L292_G296del5

c.874_887del15

1 paper

NM_002253.4

p.T298_R299ins4

c.892_896ins12

1 paper

NM_002253.4

p.G296_V297del2

c.886_890del6

1 paper

NM_002253.4

p.G296V

c.887G>T

1 paper

NM_002253.4

p.G296A

c.887G>C

1 paper

NM_002253.4

p.G296D

c.887G>A

1 paper

NM_002253.4

p.T298I

c.893C>T

1 paper

NM_002253.4

p.S283_V297del15

c.847_890del45

1 paper

NM_002253.4

p.T298T

c.894C>A