Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002253.4

p.S264F

c.791C>T

Surrounding Variants

1 paper

NM_002253.4

p.S264Y

c.791C>A

1 paper

NM_002253.4

p.S264_S265insA

c.790_794ins3

1 paper

NM_002253.4

p.S264A

c.790T>G

1 paper

NM_002253.4

p.S264T

c.790T>A

1 paper

NM_002253.4

p.P263insFs

c.788dupC

1 paper

NM_002253.4

p.S265A

c.793T>G

1 paper

NM_002253.4

p.N259_S264del6

c.775_791del18

5 papers

NM_002253.4

p.S265L

c.794C>T

1 paper

NM_002253.4

p.P263L

c.788C>T

1 paper

NM_002253.4

p.P263A

c.787C>G

1 paper

NM_002253.4

p.P263_S264ins4

c.787_791ins12

2 papers

NM_002253.4

p.P263T

c.787C>A