Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002253.4

p.E261K

c.781G>A

Surrounding Variants

1 paper

NM_002253.4

p.E261_Y262ins8

c.781_785ins24

1 paper

NM_002253.4

p.N253_W260del8

c.757_779del24

1 paper

NM_002253.4

p.L252_W260del9

c.754_779del27

2 papers

NM_002253.4

p.W260*

c.780G>A

1 paper

NM_002253.4

p.C246_N259del14

c.736_776del42

1 paper

NM_002253.4

p.E261A

c.782A>C

1 paper

NM_002253.4

p.W260S

c.779G>C

2 papers

NM_002253.4

p.W260*

c.779G>A

1 paper

NM_002253.4

p.F258_N259del2

c.772_776del6

1 paper

NM_002253.4

p.Y262_P263insAAT

c.784_788ins9

1 paper

NM_002253.4

p.W260_E261insGTT

c.778_782ins9

1 paper

NM_002253.4

p.Y262_P263ins5

c.784_788ins15