Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.D257_F258insT

c.769_773ins3

Surrounding Variants

1 paper

NM_002253.4

p.D257N

c.769G>A

1 paper

NM_002253.4

p.T250_I256del7

c.748_767del21

1 paper

NM_002253.4

p.I256_D257insFs

c.768_769insAG

1 paper

NM_002253.4

p.D257A

c.770A>C

1 paper

NM_002253.4

p.G255_I256del2

c.763_767del6

2 papers

NM_002253.4

p.I256T

c.767T>C

1 paper

NM_002253.4

p.A248_G255del8

c.742_764del24

1 paper

NM_002253.4

p.G255G

c.765G>C

1 paper

NM_002253.4

p.G255R

c.763G>C

1 paper

NM_002253.4

p.G255R

c.763G>A

1 paper

NM_002253.4

p.C246_V254del9

c.736_761del27

2 papers

NM_002253.4

p.N259Y

c.775A>T