Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002253.4

p.L228_S229insA

c.682_686ins3

Surrounding Variants

1 paper

NM_002253.4

p.V227G

c.680T>G

1 paper

NM_002253.4

p.D225_V226del2

c.673_677del6

1 paper

NM_002253.4

p.L228L

c.684G>A

1 paper

NM_002253.4

p.V227_L228insAA

c.679_683ins6

1 paper

NM_002253.4

p.D225_L228del4

c.673_683del12

2 papers

NM_002253.4

p.S229N

c.686G>A

1 paper

NM_002253.4

p.V226_V227insG

c.676_680ins3

3 papers

NM_002253.4

p.V226M

c.676G>A

1 paper

NM_002253.4

p.V227_S229del3

c.679_686del9

1 paper

NM_002253.4

p.R222_S229del8

c.664_686del24

1 paper

NM_002253.4

p.Y221_S229del9

c.661_686del27

3 papers

NM_002253.4

p.P230L

c.689C>T