Varaico: Literature-Extracted Genetic Variants

KDR

1,863 papers

RefSeq Summary

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor,...

Pfam Domains

VEGFR1-3_N_Ig-likeaa 30–128UCSCVEGFR1-3, N-terminal Ig-like domain

VEGFR-1-like_Ig-likeaa 133–218UCSCVascular endothelial growth factor receptor 1-like, Ig-like domain

igaa 232–313UCSCImmunoglobulin domain

I-setaa 332–417UCSCImmunoglobulin I-set domain

Ig_VEGFR-1-like_5thaa 418–549UCSCVEGFR-1-like, immunoglobulin-like domain

Ig_3aa 550–646UCSCImmunoglobulin domain

Gene Aliases

HGNC Name

kinase insert domain receptor

HGNC Alias Symbols

FLK1; VEGFR; VEGFR2; CD309

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002253.4

p.K4K

c.12G>A

Surrounding Variants

7 papers

NM_002253.4

p.K4N

c.12G>C

1 paper

NM_002253.4

p.K4delins

c.11delinsA

1 paper

NM_002253.4

p.K4M

c.11A>T

1 paper

NM_002253.4

p.K4Fs

c.10delinsCTCFs

1 paper

NM_002253.4

p.S3T

c.8G>C

1 paper

NM_002253.4

p.L6V

c.16C>G

1 paper

NM_002253.4

p.L6M

c.16C>A

2 papers

NM_002253.4

p.Q2R

c.5A>G

1 paper

NM_002253.4

p.Q2insFs

c.4dupC

1 paper

NM_002253.4

p.Q2*

c.4C>T

1 paper

NM_002253.4

p.M1I

c.3G>T

1 paper

NM_002253.4

p.M1_Q2insFs

c.3_4insA