Varaico: Literature-Extracted Genetic Variants

Gene:KIF2C
Variant:p.I446T

KIF2C

101 papers

RefSeq Summary

This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromos...

Pfam Domains

KIF2A-like_1staa 8–62UCSCKinesin-like protein KIF2A-like, N-terminal
Kinesinaa 264–588UCSCKinesin motor domain

Gene Aliases

HGNC Name

kinesin family member 2C

HGNC Previous Symbol

KNSL6

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_006845.4
p.I446T
c.1337T>C
Surrounding Variants
6 papers
NM_006845.4
p.I449L
c.1345A>C
1 paper
NM_006845.4
p.M451V
c.1351A>G
1 paper
NM_006845.4
p.Q428Q
c.1284G>A
1 paper
NM_006845.4
p.D424D
c.1272C>T
1 paper
NM_006845.4
p.D424G
c.1271A>G
1 paper
NM_006845.4
p.V421M
c.1261G>A
2 papers
NM_006845.4
p.R420S
c.1258C>A
1 paper
NM_006845.4
p.A463T
c.1387G>A
1 paper
NM_006845.4
p.A463V
c.1388C>T
1 paper
NM_006845.4
p.S467F
c.1400C>T
1 paper
NM_006845.4
p.A472V
c.1415C>T
1 paper
NM_006845.4
p.R483I
c.1448G>T
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