Varaico: Literature-Extracted Genetic Variants

KLF11

127 papers

RefSeq Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apopto...

Pfam Domains

zf-C2H2aa 394–418UCSCZinc finger, C2H2 type

zf-C2H2aa 424–448UCSCZinc finger, C2H2 type

zf-C2H2aa 454–476UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

KLF transcription factor 11

HGNC Previous Symbol

TIEG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_003597.5

p.D11N

c.31G>A

Surrounding Variants

1 paper

NM_003597.5

p.D11fs

c.31_32fs

1 paper

NM_003597.5

p.A14insFs

c.40_41dupGC

1 paper

NM_003597.5

p.D11_A12delFs

c.33_34delCG

1 paper

NM_003597.5

p.A12E

c.35C>A

1 paper

NM_003597.5

p.A12V

c.35C>T

1 paper

NM_003597.5

p.P9delFs

c.27delA

1 paper

NM_003597.5

p.P9fs

c.25_26fs

1 paper

NM_003597.5

p.A14_V15Splc

c.42+3G>C

1 paper

NM_003597.5

p.D5G

c.14A>G

1 paper

NM_003597.5

p.T3A

c.7A>G

1 paper

NM_003597.5

p.M1T

c.2T>C

1 paper

NM_003597.5

p.V15fs

c.43_44fs