Varaico: Literature-Extracted Genetic Variants

KLF11

127 papers

RefSeq Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apopto...

Pfam Domains

zf-C2H2aa 394–418UCSCZinc finger, C2H2 type

zf-C2H2aa 424–448UCSCZinc finger, C2H2 type

zf-C2H2aa 454–476UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

KLF transcription factor 11

HGNC Previous Symbol

TIEG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003597.5

p.D194Y

c.580G>T

Surrounding Variants

4 papers

NM_003597.5

p.P193T

c.577C>A

1 paper

NM_003597.5

p.S200N

c.599G>A

1 paper

NM_003597.5

p.E202K

c.604G>A

1 paper

NM_003597.5

p.E202D

c.606A>T

1 paper

NM_003597.5

p.A184V

c.551C>T

1 paper

NM_003597.5

p.A184P

c.550G>C

2 papers

NM_003597.5

p.S182R

c.546C>A

2 papers

NM_003597.5

p.S182R

c.546C>G

2 papers

NM_003597.5

p.S182R

c.544A>C

1 paper

NM_003597.5

p.E181K

c.541G>A

1 paper

NM_003597.5

p.T179fs

c.535_536fs

1 paper

NM_003597.5

p.H210_Q215del0

c.630_644del15