Varaico: Literature-Extracted Genetic Variants

KLF11

127 papers

RefSeq Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apopto...

Pfam Domains

zf-C2H2aa 394–418UCSCZinc finger, C2H2 type

zf-C2H2aa 424–448UCSCZinc finger, C2H2 type

zf-C2H2aa 454–476UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

KLF transcription factor 11

HGNC Previous Symbol

TIEG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_001177716.2

p.E248K

c.742G>A

NM_003597.5

p.E265K

c.793G>A

Surrounding Variants

1 paper

NM_003597.5

p.Y264fs

c.790_791fs

1 paper

NM_003597.5

p.Y264delFs

c.791delA

2 papers

NM_003597.5

p.P261L

c.782C>T

1 paper

NM_003597.5

p.Q257R

c.770A>G

1 paper

NM_003597.5

p.P274S

c.820C>T

1 paper

NM_003597.5

p.P274L

c.821C>T

2 papers

NM_003597.5

p.G251E

c.752G>A

1 paper

NM_003597.5

p.P283P

c.849C>T

1 paper

NM_003597.5

p.K246fs

c.736_737fs

1 paper

NM_003597.5

p.K246_G247delFs

c.736_739del4

1 paper

NM_003597.5

p.T244I

c.731C>T

1 paper

NM_003597.5

p.L286F

c.856C>T