Varaico: Literature-Extracted Genetic Variants

KLF11

127 papers

RefSeq Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apopto...

Pfam Domains

zf-C2H2aa 394–418UCSCZinc finger, C2H2 type

zf-C2H2aa 424–448UCSCZinc finger, C2H2 type

zf-C2H2aa 454–476UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

KLF transcription factor 11

HGNC Previous Symbol

TIEG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003597.5

p.T449A

c.1345A>G

Surrounding Variants

1 paper

NM_001177716.2

p.T432_G433delFs

c.1296_1297delAG

1 paper

NM_003597.5

p.H448fs

c.1342_1343fs

1 paper

NM_003597.5

p.H448_T449delFs

c.1342_1345del4

3 papers

NM_003597.5

p.K453del1

c.1357_1358delAAG

1 paper

NM_003597.5

p.R446G

c.1336A>G

1 paper

NM_001177716.2

p.K435fs

c.1303_1304fs

1 paper

NM_003597.5

p.K453*

c.1357A>T

1 paper

NM_003597.5

p.R461*

c.1381C>T

6 papers

NM_003597.5

p.R461Q

c.1382G>A

1 paper

NM_003597.5

p.F435Y

c.1304T>A

1 paper

NM_003597.5

p.F435fs

c.1303_1304fs

1 paper

NM_003597.5

p.F435delFs

c.1303delT