Varaico: Literature-Extracted Genetic Variants

KLF11

127 papers

RefSeq Summary

The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apopto...

Pfam Domains

zf-C2H2aa 394–418UCSCZinc finger, C2H2 type

zf-C2H2aa 424–448UCSCZinc finger, C2H2 type

zf-C2H2aa 454–476UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

KLF transcription factor 11

HGNC Previous Symbol

TIEG2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_003597.5

p.G484S

c.1450G>A

Surrounding Variants

2 papers

NM_003597.5

p.P483S

c.1447C>T

1 paper

NM_003597.5

p.I482insFs

c.1445_1446ins5

1 paper

NM_003597.5

p.I482fs

c.1444_1445fs

1 paper

NM_003597.5

p.E488G

c.1463A>G

1 paper

NM_003597.5

p.M477R

c.1430T>G

1 paper

NM_003597.5

p.K471R

c.1412A>G

1 paper

NM_003597.5

p.S500R

c.1498A>C

1 paper

NM_003597.5

p.S500R

c.1500C>A

1 paper

NM_003597.5

p.S500R

c.1500C>G

3 papers

NM_003597.5

p.R465H

c.1394G>A

6 papers

NM_003597.5

p.R461Q

c.1382G>A

1 paper

NM_003597.5

p.R461*

c.1381C>T