KLF transcription factor 8

BKLF3

ZNF741

DXS741

Kruppel like factor 8

Krueppel-like factor 8

Basic krueppel-like factor 3

Zinc finger protein 741

This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009].

Varaico: Literature-Extracted Genetic Variants

KLF8

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols