Varaico: Literature-Extracted Genetic Variants

KNDC1

136 papers

RefSeq Summary

The protein encoded by this gene is a Ras guanine nucleotide exchange factor that appears to negatively regulate dendritic growth in the brain. Knockdown of this gene in senescent umbilical vein endot...

Pfam Domains

KINDaa 37–183UCSCKinase non-catalytic C-lobe domain

RasGEF_Naa 1249–1348UCSCRasGEF N-terminal motif

RasGEFaa 1471–1678UCSCRasGEF domain

Gene Aliases

HGNC Name

kinase non-catalytic C-lobe domain containing 1

HGNC Previous Symbols

RASGEF2; C10orf23

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_152643.8

p.G116R

c.346G>A

Surrounding Variants

1 paper

NM_152643.8

p.G116R

c.346G>C

1 paper

NM_152643.8

p.G116V

c.347G>T

1 paper

NM_152643.8

p.N88N

c.264C>T

1 paper

NM_152643.8

p.N88Y

c.262A>T

1 paper

NM_152643.8

p.T81R

c.242C>G

1 paper

NM_152643.8

p.T81M

c.242C>T

1 paper

NM_152643.8

p.V69G

c.206T>G

1 paper

NM_152643.8

p.S51S

c.153C>T

1 paper

NM_152643.8

p.R48R

c.144C>G

1 paper

NM_152643.8

p.R48R

c.144C>T

1 paper

NM_152643.8

p.R48C

c.142C>T

1 paper

NM_152643.8

p.R46Q

c.137G>A