Varaico: Literature-Extracted Genetic Variants

KNDC1

136 papers

RefSeq Summary

The protein encoded by this gene is a Ras guanine nucleotide exchange factor that appears to negatively regulate dendritic growth in the brain. Knockdown of this gene in senescent umbilical vein endot...

Pfam Domains

KINDaa 37–183UCSCKinase non-catalytic C-lobe domain

RasGEF_Naa 1249–1348UCSCRasGEF N-terminal motif

RasGEFaa 1471–1678UCSCRasGEF domain

Gene Aliases

HGNC Name

kinase non-catalytic C-lobe domain containing 1

HGNC Previous Symbols

RASGEF2; C10orf23

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_152643.8

p.P813P

c.2439C>T

Surrounding Variants

1 paper

NM_152643.8

p.A807T

c.2419G>A

2 papers

NM_152643.8

p.V806D

c.2417T>A

2 papers

NM_152643.8

p.V806delins

c.2417_2418delinsAC

1 paper

NM_152643.8

p.P801L

c.2402C>T

1 paper

NM_152643.8

p.P798L

c.2393C>T

1 paper

NM_152643.8

p.P832L

c.2495C>T

1 paper

NM_152643.8

p.G779D

c.2336G>A

1 paper

NM_152643.8

p.A777G

c.2330C>G

1 paper

NM_152643.8

p.A777T

c.2329G>A

1 paper

NM_152643.8

p.A852_R855del4

c.2554_2564del12

1 paper

NM_152643.8

p.R855H

c.2564G>A

1 paper

NM_152643.8

p.Q858Q

c.2574G>A