Varaico: Literature-Extracted Genetic Variants

KNDC1

136 papers

RefSeq Summary

The protein encoded by this gene is a Ras guanine nucleotide exchange factor that appears to negatively regulate dendritic growth in the brain. Knockdown of this gene in senescent umbilical vein endot...

Pfam Domains

KINDaa 37–183UCSCKinase non-catalytic C-lobe domain

RasGEF_Naa 1249–1348UCSCRasGEF N-terminal motif

RasGEFaa 1471–1678UCSCRasGEF domain

Gene Aliases

HGNC Name

kinase non-catalytic C-lobe domain containing 1

HGNC Previous Symbols

RASGEF2; C10orf23

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_152643.8

p.R1027Q

c.3080G>A

Surrounding Variants

1 paper

NM_152643.8

p.R1027W

c.3079C>T

1 paper

NM_152643.8

p.D1023D

c.3069C>T

1 paper

NM_152643.8

p.D1023G

c.3068A>G

1 paper

NM_152643.8

p.S1018L

c.3053C>T

1 paper

NM_152643.8

p.Q1037H

c.3111G>C

1 paper

NM_152643.8

p.Q1037H

c.3111G>T

1 paper

NM_152643.8

p.R1038_V1040del3

c.3112_3119del9

1 paper

NM_152643.8

p.V1040I

c.3118G>A

1 paper

NM_152643.8

p.A1002V

c.3005C>T

2 papers

NM_152643.8

p.R1055W

c.3163C>T

1 paper

NM_152643.8

p.A1057V

c.3170C>T

1 paper

NM_152643.8

p.R1071R

c.3213G>A