Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_004690.4

p.R1125H

c.3374G>A

Surrounding Variants

1 paper

NM_004690.4

p.R1125C

c.3373C>T

1 paper

NM_004690.4

p.N1117H

c.3349A>C

1 paper

NM_004690.4

p.Q1116E

c.3346C>G

1 paper

NM_004690.4

p.D1114Y

c.3340G>T

1 paper

NM_004690.4

p.S1111A

c.3331T>G

1 paper

NM_004690.4

p.Q1109H

c.3327G>T

1 paper

NM_004690.4

p.Q1109H

c.3327G>C

1 paper

NM_004690.4

p.G1106A

c.3317G>C

1 paper

NM_004690.4

p.I1097V

c.3289A>G

1 paper

NM_004690.4

p.P1094Q

c.3281C>A

1 paper

NM_004690.4

p.P1094T

c.3280C>A

1 paper

NM_004690.4

p.D1086V

c.3257A>T