Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.F1075L

c.3223T>C

Surrounding Variants

1 paper

NM_004690.4

p.F1075L

c.3225C>G

1 paper

NM_004690.4

p.F1075L

c.3225C>A

1 paper

NM_004690.4

p.T1079A

c.3235A>G

1 paper

NM_004690.4

p.R1081Q

c.3242G>A

2 papers

NM_004690.4

p.R1082K

c.3245G>A

2 papers

NM_004690.4

p.D1086Y

c.3256G>T

1 paper

NM_004690.4

p.D1086V

c.3257A>T

2 papers

NM_004690.4

p.V1057A

c.3170T>C

1 paper

NM_004690.4

p.P1094T

c.3280C>A

1 paper

NM_004690.4

p.P1094Q

c.3281C>A

1 paper

NM_004690.4

p.E1055A

c.3164A>C

1 paper

NM_004690.4

p.I1097V

c.3289A>G