Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.P1041L

c.3122C>T

Surrounding Variants

1 paper

NM_004690.4

p.P1041S

c.3121C>T

1 paper

NM_004690.4

p.D1043N

c.3127G>A

1 paper

NM_004690.4

p.P1044H

c.3131C>A

2 papers

NM_004690.4

p.N1038H

c.3112A>C

1 paper

NM_004690.4

p.D1035E

c.3105T>A

1 paper

NM_004690.4

p.D1035G

c.3104A>G

1 paper

NM_004690.4

p.D1035A

c.3104A>C

1 paper

NM_004690.4

p.I1030V

c.3088A>G

2 papers

NM_004690.4

p.P1028A

c.3082C>G

1 paper

NM_004690.4

p.P1028T

c.3082C>A

1 paper

NM_004690.4

p.E1055A

c.3164A>C

2 papers

NM_004690.4

p.V1057A

c.3170T>C