Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_004690.4

p.S1023C

c.3068C>G

Surrounding Variants

1 paper

NM_004690.4

p.Q1021delFs

c.3061_3062delTG

1 paper

NM_004690.4

p.Q1021fs

c.3061_3062fs

4 papers

NM_004690.4

p.R1020T

c.3059G>C

2 papers

NM_004690.4

p.P1028A

c.3082C>G

1 paper

NM_004690.4

p.P1028T

c.3082C>A

1 paper

NM_004690.4

p.I1030V

c.3088A>G

3 papers

NM_004690.4

p.F1015L

c.3045C>G

3 papers

NM_004690.4

p.F1015L

c.3045C>A

3 papers

NM_004690.4

p.F1015L

c.3043T>C

1 paper

NM_004690.4

p.D1014D

c.3042C>T

1 paper

NM_004690.4

p.D1035G

c.3104A>G

1 paper

NM_004690.4

p.D1035A

c.3104A>C