Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_004690.4

p.R995C

c.2983C>T

Surrounding Variants

1 paper

NM_004690.4

p.R995G

c.2983C>G

1 paper

NM_004690.4

p.R995H

c.2984G>A

2 papers

NM_004690.4

p.D994N

c.2980G>A

1 paper

NM_004690.4

p.N999D

c.2995A>G

1 paper

NM_004690.4

p.N999T

c.2996A>C

1 paper

NM_004690.4

p.R990L

c.2969G>T

2 papers

NM_004690.4

p.R990Q

c.2969G>A

1 paper

NM_004690.4

p.C989F

c.2966G>T

1 paper

NM_004690.4

p.I986S

c.2957T>G

1 paper

NM_004690.4

p.K1005R

c.3014A>G

1 paper

NM_004690.4

p.K1005N

c.3015A>T

1 paper

NM_004690.4

p.K1005N

c.3015A>C