Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.R838fs

c.2512_2513fs

Surrounding Variants

1 paper

NM_004690.4

p.R838C

c.2512C>T

2 papers

NM_004690.4

p.R838G

c.2512C>G

1 paper

NM_004690.4

p.D837insFs

c.2511dupT

2 papers

NM_004690.4

p.R838S

c.2512C>A

1 paper

NM_004690.4

p.R838H

c.2513G>A

2 papers

NM_004690.4

p.D837H

c.2509G>C

1 paper

NM_004690.4

p.G840V

c.2519G>T

2 papers

NM_004690.4

p.H841Y

c.2521C>T

1 paper

NM_004690.4

p.I842T

c.2525T>C

1 paper

NM_004690.4

p.L844M

c.2530T>A

1 paper

NM_004690.4

p.D832Y

c.2494G>T

2 papers

NM_004690.4

p.K830R

c.2489A>G