Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.D828N

c.2482G>A

Surrounding Variants

2 papers

NM_004690.4

p.R827delFs

c.2480delC

2 papers

NM_004690.4

p.R827T

c.2480G>C

1 paper

NM_004690.4

p.R827K

c.2480G>A

1 paper

NM_004690.4

p.R827fs

c.2479_2480fs

1 paper

NM_004690.4

p.K830E

c.2488A>G

2 papers

NM_004690.4

p.K830R

c.2489A>G

1 paper

NM_004690.4

p.F824L

c.2472T>G

1 paper

NM_004690.4

p.F824L

c.2472T>A

1 paper

NM_004690.4

p.F824L

c.2470T>C

1 paper

NM_004690.4

p.D832Y

c.2494G>T

2 papers

NM_004690.4

p.G823V

c.2468G>T

2 papers

NM_004690.4

p.H820R

c.2459A>G