Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.E802K

c.2404G>A

Surrounding Variants

2 papers

NM_004690.4

p.S803T

c.2408G>C

2 papers

NM_004690.4

p.A805V

c.2414C>T

1 paper

NM_004690.4

p.R806*

c.2416C>T

2 papers

NM_004690.4

p.R806P

c.2417G>C

1 paper

NM_004690.4

p.A810S

c.2428G>T

1 paper

NM_004690.4

p.L793Q

c.2378T>A

1 paper

NM_004690.4

p.L793I

c.2377C>A

1 paper

NM_004690.4

p.S792I

c.2375G>T

1 paper

NM_004690.4

p.M790I

c.2370G>T

1 paper

NM_004690.4

p.M790I

c.2370G>C

1 paper

NM_004690.4

p.M790I

c.2370G>A

1 paper

NM_004690.4

p.T813I

c.2438C>T