Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.M782I

c.2346G>C

Surrounding Variants

1 paper

NM_004690.4

p.M782I

c.2346G>T

1 paper

NM_004690.4

p.M782I

c.2346G>A

1 paper

NM_004690.4

p.D783N

c.2347G>A

1 paper

NM_004690.4

p.D783V

c.2348A>T

1 paper

NM_004690.4

p.P786T

c.2356C>A

2 papers

NM_004690.4

p.G787V

c.2360G>T

1 paper

NM_004690.4

p.G787A

c.2360G>C

1 paper

NM_004690.4

p.N777K

c.2331T>G

1 paper

NM_004690.4

p.N777K

c.2331T>A

1 paper

NM_004690.4

p.D789H

c.2365G>C

2 papers

NM_004690.4

p.M790T

c.2369T>C

1 paper

NM_004690.4

p.M790I

c.2370G>T