Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.K734R

c.2201A>G

Surrounding Variants

1 paper

NM_004690.4

p.R737*

c.2209C>T

2 papers

NM_004690.4

p.R737Q

c.2210G>A

1 paper

NM_004690.4

p.K738N

c.2214G>T

1 paper

NM_004690.4

p.K738N

c.2214G>C

1 paper

NM_004690.4

p.L742V

c.2224C>G

1 paper

NM_004690.4

p.L742P

c.2225T>C

1 paper

NM_004690.4

p.L743F

c.2227C>T

1 paper

NM_004690.4

p.R744L

c.2231G>T

2 papers

NM_004690.4

p.R744Q

c.2231G>A

1 paper

NM_004690.4

p.N745S

c.2234A>G

2 papers

NM_004690.4

p.A748T

c.2242G>A

2 papers

NM_004690.4

p.V719I

c.2155G>A