Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_004690.4

p.R694C

c.2080C>T

Surrounding Variants

1 paper

NM_004690.4

p.R694S

c.2080C>A

2 papers

NM_004690.4

p.R694H

c.2081G>A

1 paper

NM_004690.4

p.Y692H

c.2074T>C

3 papers

NM_004690.4

p.R697G

c.2089A>G

1 paper

NM_004690.4

p.R697fs

c.2089_2090fs

2 papers

NM_004690.4

p.S690A

c.2068T>G

1 paper

NM_004690.4

p.K702M

c.2105A>T

2 papers

NM_004690.4

p.M704V

c.2110A>G

1 paper

NM_004690.4

p.R682T

c.2045G>C

1 paper

NM_004690.4

p.V706M

c.2116G>A

1 paper

NM_004690.4

p.I708M

c.2124A>G

2 papers

NM_004690.4

p.Q678H

c.2034G>T