Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_004690.4

p.M669I

c.2007G>T

Surrounding Variants

1 paper

NM_004690.4

p.M669I

c.2007G>C

1 paper

NM_004690.4

p.M669I

c.2007G>A

3 papers

NM_004690.4

p.R670W

c.2008C>T

1 paper

NM_004690.4

p.R670Q

c.2009G>A

1 paper

NM_004690.4

p.E667K

c.1999G>A

1 paper

NM_004690.4

p.Q663fs

c.1987_1988fs

1 paper

NM_004690.4

p.Q663L

c.1988A>T

1 paper

NM_004690.4

p.K662insFs

c.1986dupA

1 paper

NM_004690.4

p.K662N

c.1986A>T

1 paper

NM_004690.4

p.K662N

c.1986A>C

1 paper

NM_004690.4

p.K662fs

c.1984_1985fs

1 paper

NM_004690.4

p.K662fs

c.1984_1985fs