Varaico: Literature-Extracted Genetic Variants

LATS1

253 papers

RefSeq Summary

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is pho...

Pfam Domains

UBAaa 101–138UCSCUBA/TS-N domain

Pkinaseaa 705–866UCSCProtein kinase domain

Pkinaseaa 896–1010UCSCProtein kinase domain

Pkinase_Caa 1030–1080UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

large tumor suppressor kinase 1

HGNC Alias Symbol

WARTS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_004690.4

p.F641L

c.1921T>C

Surrounding Variants

3 papers

NM_004690.4

p.F641L

c.1923C>G

3 papers

NM_004690.4

p.F641L

c.1923C>A

1 paper

NM_004690.4

p.M643I

c.1929G>T

1 paper

NM_004690.4

p.M643I

c.1929G>C

1 paper

NM_004690.4

p.M643I

c.1929G>A

1 paper

NM_004690.4

p.E644G

c.1931A>G

1 paper

NM_004690.4

p.Q632K

c.1894C>A

2 papers

NM_004690.4

p.V650A

c.1949T>C

1 paper

NM_004690.4

p.R630H

c.1889G>A

1 paper

NM_004690.4

p.H654Y

c.1960C>T

1 paper

NM_004690.4

p.R627S

c.1881G>T

1 paper

NM_004690.4

p.R627S

c.1881G>C